By reading this case study, you will discover:
- Why leveraging cause-and-effect analysis is imperative for advancing drug target selection
- How a robust proof of mechanism enhances the likelihood of drug discovery projects advancing from clinical development to market launch
- Two detailed examples of applying groundbreaking Natural Language Processing-fueled technology to understanding complex biological mechanisms: Investigating the application of roflumilast, a drug approved for treating chronic obstructive pulmonary disease (COPD), in treating Non-Cystic Fibrosis Bronchiectasis. Examining the observed correlation between obesity and increased expression of the protein LCN2, a relationship currently lacking a direct cause-and-effect rationale.
