Enhancing Drug Development Success Through Strategic Focus on Mechanism of Action and Explainability

By reading this case study, you will discover:

  • Why leveraging cause-and-effect analysis is imperative for advancing drug target selection
  • How a robust proof of mechanism enhances the likelihood of drug discovery projects advancing from clinical development to market launch
  • Two detailed examples of applying groundbreaking Natural Language Processing-fueled technology to understanding complex biological mechanisms: Investigating the application of roflumilast, a drug approved for treating chronic obstructive pulmonary disease (COPD), in treating Non-Cystic Fibrosis Bronchiectasis. Examining the observed correlation between obesity and increased expression of the protein LCN2, a relationship currently lacking a direct cause-and-effect rationale.
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